29 research compounds. Evidence-graded. Source-linked.

The Immortal Peps library gathers in-depth guides across tissue repair, the growth hormone axis, longevity, mitochondrial biology, cognition, immunity, and endocrine signalling. Each profile carries an evidence badge so the strength of the literature is visible at a glance.

29 research compounds. Evidence-graded. Source-linked.

BPC-157

Synthetic pentadecapeptide studied for angiogenesis, NO-system modulation, and systemic cytoprotection across preclinical models.

TB-500

Thymosin Beta-4 fragment investigated for actin regulation, cell migration, and cytoskeletal dynamics.

BPC-157 + TB-500

Combined tissue-repair peptides studied for complementary mechanisms — the synergy hypothesis, examined critically.

GHK-Cu

Copper-binding tripeptide with topical and systemic research into collagen, gene expression, and dermal remodelling.

Thymosin Alpha-1

Immunomodulatory peptide studied in immune restoration research — approved in certain hepatitis and oncology indications.

LL-37

Cathelicidin-derived antimicrobial peptide studied in innate immunity and tissue inflammation research.

GH pulsatility & endocrine signalling

Compounds acting on the growth hormone secretagogue receptor (GHSR), GHRH pathways, and downstream IGF-1 modulation.

Ipamorelin

Selective GHSR-1a agonist studied for targeted GH release with minimal cortisol, ACTH and prolactin effect.

CJC-1295 (no DAC)

Modified GHRH analogue studied for sustained GH release via albumin conjugation in long-acting form.

Hexarelin

Synthetic hexapeptide GHSR agonist studied for GH release and CD36 receptor activity.

GHRP-6

Growth hormone releasing hexapeptide studied for ghrelin-receptor agonism and appetite signalling.

GHRP-2

Synthetic ghrelin mimetic studied for GH pulse modulation and gastric motility effects.

Tesamorelin

FDA-approved GHRH analogue studied for visceral adiposity reduction in HIV-associated lipodystrophy.

Glucose regulation, energy, and bioenergetics

Compounds studied for insulin sensitivity, mitochondrial function, and the cellular energy economy.

MOTS-c

Mitochondrial-encoded peptide studied for AMPK activation, insulin sensitivity, and metabolic stress response.

Semaglutide

GLP-1 receptor agonist with extensive Phase 3 data — covered here as the metabolic research baseline.

Tirzepatide

Dual GIP/GLP-1 receptor agonist studied for glycaemic control and weight loss in T2D and obesity trials.

Retatrutide

Triple-agonist (GIP/GLP-1/glucagon) currently in Phase 2 trials for obesity and metabolic disease.

5-Amino-1MQ

Small-molecule NNMT inhibitor studied for metabolic rate, NAD+ levels, and adipose tissue browning.

SS-31 (Elamipretide)

Mitochondria-targeted tetrapeptide studied for cardiolipin stabilisation and oxidative phosphorylation efficiency.

Cellular ageing & healthspan

Compounds researched across the hallmarks of ageing — telomere attrition, mitochondrial dysfunction, and senescence.

Epithalon

Tetrapeptide studied for telomerase expression, pineal regulation, and cellular senescence modulation.

Follistatin 344

Activin-binding glycoprotein studied for myostatin antagonism in muscle-wasting research models.

NAD+ (NMN / NR)

NAD+ precursors studied for sirtuin activation, mitochondrial biogenesis, and age-related metabolic decline.

Rapamycin (off-label)

mTOR inhibitor studied in the Dog Aging Project and PEARL trial for lifespan extension outcomes.

Metformin

Biguanide antidiabetic studied in the TAME trial for age-related disease incidence (underway).

Neuroprotection & cognitive research

Compounds studied for neuropeptide signalling, BDNF expression, and stress-axis regulation.

Semax

ACTH(4-7) analogue studied for BDNF and NGF expression across cognitive and neuroprotection research.

Selank

Tuftsin analogue studied for serotonin and BDNF modulation, and GABAergic anxiolytic mechanism.

Dihexa

Angiotensin IV analogue studied for HGF/c-Met receptor binding and synaptic plasticity research.

Cerebrolysin

Porcine-brain-derived peptide mixture studied for neurotrophic factor mimicry in stroke recovery.

Endocrine & melanocortin signalling

Compounds acting on melanocortin receptors and the HPG axis.

Melanotan I

α-MSH analogue studied for MC1R-mediated melanogenesis and UV-protective photobiology research.

Melanotan II

Non-selective MCR agonist studied for MC3R/MC4R sexual arousal research and pigmentation effects.

Bremelanotide

FDA-approved MC4R agonist for hypoactive sexual desire disorder in premenopausal women.

Kisspeptin

Neuropeptide studied for GnRH pulse generation and HPG-axis mediated reproductive hormone release.

How we grade evidence.

Every profile carries an evidence badge — Preclinical, Human Trials, or Mixed. We cite primary sources, not blogs or forums.