Growth Hormone
Peptides
Compound profile

GHRP-2: Synthetic Ghrelin Mimetic

On this page

What it is

GHRP-2 is a synthetic hexapeptide GHS that activates GHSR-1a, with slightly higher potency than GHRP-6 in some assays and pronounced orexigenic effects.

Evidence snapshot

Category: Growth Hormone. Status: Preclinical. See the references section below for the underlying primary sources.

Mechanism

Activates GHSR-1a for GH release. Appetite stimulation is significant, limiting clinical utility. Gastric motility effects are also documented.

Key research findings

GH release demonstrated across multiple species. Appetite and gastric motility effects studied in human and animal populations as proof-of-concept for ghrelin pharmacology.

Limits of the evidence

Off-label use widespread. Significant appetite effects complicate selectivity. Cortisol and prolactin increases at higher doses. Not approved for any human indication.

Continue reading

Tissue Repair

BPC-157

Synthetic pentadecapeptide derived from a gastric juice protein, studied across hundreds of preclinical reports for tissue regeneration and cytoprotection.
Read Guid
Tissue Repair

TB-500 (Thymosin Beta-4 fragment)

Synthetic fragment of Thymosin Beta-4, a 43-amino-acid peptide investigated for its role in actin regulation, cell migration, and wound healing.
Read Guid
Peptide Protocols

BPC-157 + TB-500

Combined tissue-repair peptides with complementary mechanisms — the synergy hypothesis examined critically against the available preclinical record.
Read Guid
Growth Hormone · Research

Ipamorelin

Selective pentapeptide agonist of the growth hormone secretagogue receptor (GHSR-1a) studied for targeted GH release with minimal effect on cortisol, ACTH and prolactin.
Read Guid